During the procedure mice should be monitored mainly for anesthesia body temperature and cardiovascular and respiratory function. Which statement is true about a records management system for clinical assessments of rodents.
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Which statement is true about body temperature measurement in rodents. Using these rats is sometimes desirable in scientific studies when genetic heterogeneity differences is not a concern. 16778595111119137 the technique used to measure body temperature is critical to the interpretation of an experiment due to the heterogeneity of temperature in different locations of the animals body ranging from the temperature of the tail to the animals true core temperature. Which statement is true about supporting body temperature in anesthetized rodents. Start studying exercise 4. Genetically dissimilar animals males and females that are not related are mated. Many rodent studies have demonstrated different experimental outcomes due to differences in body temperature under anesthesia including studies of the heart brain liver and urogenital system.
Learn vocabulary terms and more with flashcards games and other study tools. Although previous studies suggest that rectal measurement is stressful and results in long lasting elevations in body temperatures we evaluated how this procedure affects brain muscle skin and core temperatures measured with chronically implanted thermocouple electrodes in rats. During the procedure mice should be monitored mainly for depth of anesthesia cardiovascular and respiratory function. Which statement is true regarding care procedures for mice undergoing surgery. Rectal probe thermometry is commonly used to measure body core temperature in rodents because of its ease of use. On the other hand taking rectal temperature every hour suppressed the circadian rhythm of intraperitoneal temperature.
Outbred stock tend to be more healthy and produce more young also called outbred vigor. Heat sources should be modulated to a safe temperature. In 1962 miles recorded temperature in rats by radio transmitters. Lung function is a relevant endpoint in pharmacological studies eg in models for asthma copd or infection in safety pharmacological studies performed according to the ich guideline s7a core battery part lung and follow up and finally in toxicological studies particularly if the airways are in the focus of interest. Among studies involving core and surface temperature measurements in mice the surface temperature is on average 257 c 34 c or 23 c lower than core temperature depending on the site. Which statement is true regarding care procedures for mice undergoing surgery.
According to the avma guidelines which statement is true for the use of co2 as a euthanasia agent of mice. Lung function measurement techniques for rodents an overview. In unhandled rats day temperature was about 357c and nocturnal temperature about 2c higher fig.